Dr Sankar Subramanian

Accessibility links

Dr Sankar Subramanian

Breadcrumbs

Research areas

  • population genomics
  • molecular evolution
  • genome medicine
  • ancient DNA
  • bioinformatics

Sankar Subramanian joined USC as a Senior Research Fellow in March 2017. Prior to this he worked at the Australian Research Centre for Human Evolution, Griffith University. His research primarily centers around the question of, how does genetic drift influence mutations. He worked on a number of research projects to investigate the interaction between drift and mutations, which include the evolution of codon usage bias in animal genomes, temporal patterns of deleterious mutations in humans and penguins, difference in the allele frequencies of polymorphisms in global human populations. He has developed methods to identify and quantify deleterious mutations in human populations.

Sankar Subramanian is also interested in estimating rates of mutations and divergence times between species and populations. His research also focuses on studying ancient genomes to understand the past demographic history of vertebrates including ancient penguins, tuatara (a New Zealand reptile), moa (an extinct bird) and ancient humans. Furthermore, he is investigating the population history, mutational load and admixture patterns of modern and ancient Aboriginal Australians. At USC, he has started working on the conservation genomics of Australian Dingoes.

Recent key publications
  1. Malaspinas, A., Westaway, M.C., Muller, C., Sousa, V.C., Lao, O., Alves, I., Bergström, A., Athanasiadis, G., Cheng, J.Y., Crawford, J.E., Heupink, T.H., Macholdt, E., Peischl, S., Rasmussen, S., Schiffels, S., Subramanian, S., (60 more authors) (2016) A Genomic History of Aboriginal Australia. Nature 538: 207-214. - Joint second author
  2. Heupink, T., Subramanian, S., Wright, J.L., Endicott P, Westaway, C.M., Huynen, L., Parson W., Millar, C.D., Willerslev, E. and Lambert. D.M. (2016) Ancient mitochondrial DNA sequences from the First Australians revisited. Proceedings of the National Academy of Sciences USA 113: 6892-6897.
  3. Subramanian, S. (2016) The effects of sample size on population genomic analyses – implications for the tests of neutrality. BMC Genomics 17:123 (13 pages).
  4. Subramanian, S. (2016) Europeans have a higher proportion of high-frequency deleterious variants than Africans. Human Genetics 135: 1-7.
  5. Subramanian, S. (2015) Using the plurality of codon positions to identify deleterious variants in human exomes. Bioinformatics 31: 301-305.
  6. Jarvis, E.D., Mirarab, S., Aberer, A.J., Li, B., Houde, P., Li, C., Ho, S.Y.W., Faircloth, B.C., Nabholz, B., Howard, J.T., Suh, A., Weber, C.C., da Fonseca, R.R., Li, J., Zhang, F., Li, H., Zhou, L., Narula, N., Liu, L., Ganapathy, G., Boussau, B., Bayzid, M.S., Zavidovych, V., Subramanian, S., (75 more authors) (2014). Whole genome analyses resolve the early branches in the tree of life of modern birds. Science 346: 1320-1331.
Research grants

Investigators

Grant

Year

Amount

Title

Subramanian S, Lambert D, Miller A, Westaway M, Li R

ARC Linkage

2016-2019

$178,969

The effect of genomic variants on Indigenous health

Lambert D, Subramanian S, Westaway M, Willerslev E, Thangaraj K, Li R

ARC Linkage

2015-2018

$570,000

Investigating Holocene India - Australia Connections using Ancient Genomics

Westaway M, Wright D, Lambert D, Miller A, Fry B, Subramanian S, Collard M, Li R, Willerslev E

ARC Linkage

2014-2017

$740,880

Establishing the provenance of Torres Strait Islander remains: genetics, craniometrics and isotopes

Back to top

Searching {{ model.SearchType }} for "{{ model.Query }}" returned more than {{ model.MaxResults }} results.
The top {{ model.MaxResults }} of {{ model.TotalItems }} are shown below, ordered by relevance ({{ model.TotalSeconds }} seconds)

Searching {{ model.SearchType }} for "{{ model.Query }}" returned {{ model.TotalItems }} results, ordered by relevance ({{ model.TotalSeconds }} seconds)

Searching {{ model.SearchType }} for "{{ model.Query }}" returned no results.

No search results found for