About the study - Malaria Treatment - University of the Sunshine Coast, Queensland, Australia

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About the study - Malaria Treatment

Thank you for registering your interest in our healthy volunteers malaria study. A member of the research team will be in touch within 2 business days to go through the study with you.

What is the study for?

This study involves being infected with a very low dose of malaria parasites and will investigate whether a single low oral dose of an anti-malarial drug is able to clear malaria parasites from the blood.

What's involved?

The study is a Phase I clinical trial involving overnight confinement at our Phase I clinical trial centre.

  • 2 screening visits
  • Initiation of malaria infection
  • Follow-up phone call and clinic visits to monitor malaria infection
  • 5 days (and 4 nights) confinement for administration of study treatment
  • Medical assessments and blood draws on clinic visits and during confinement
  • Administration of registered, TGA-approved, commercially available, antimalarial drug/s
  • Food is provided, as well as TV, WiFi and entertainment

This is an open label study, which means you will receive the study treatment.

The anti-malarial medication used in this trial has already been registered and approved for two purposes in Australia by the Therapeutic Goods Administration (TGA), an organisation responsible for regulating medicines in Australia. This study will investigate whether a single low oral dose of this anti-malarial drug is able to clear malaria parasites from the blood.

At the end of the study, or earlier if required you will be treated with registered, TGA-approved, commercially available, antimalarial drug. This treatment is compulsory to make sure that all malaria parasites are cleared from your body. Sometimes another antimalarial drug will be required to ensure you cannot spread malaria to mosquitoes.

The research team will sit down with you at the screening visit and go through the study criteria, as well as your medical history and current and past medications. There will be some blood tests and medical examinations to help determine your eligibility for the study.

You will be required to present a valid form of ID at each visit.

All study procedures are at no cost to you, and you will receive approximately $5150 for your time and travel expenses for completing the entire study.

Key Dates

Participants must be available for the following dates:

Screening: 1 day in the week commencing 26th October
Eligibility Visit: Saturday 31st October
Clinic Visits: 7th November (morning), 8th to 10th November (morning and evening visits each day)
Overnight Stays: 11th to 15th November
Clinic Visits: 15th November (evening), 16th November to 21st December (visits 3 times per week)
End of Study: 22nd December

Where can I find more information?

More information can be requested by contacting the research site to the right. Alternatively, the research team will be more than happy to answer any questions you may have when they call.

HREC approval: QIMR Human Research Ethics Committee