Investigational respiratory 3-in-one vaccine - clinical trial begins in Brisbane | UniSC | University of the Sunshine Coast, Queensland, Australia

Accessibility links

Investigational respiratory 3-in-one vaccine - clinical trial begins in Brisbane

12 Jan 2023

The University of the Sunshine Coast will lead trials in Brisbane for an investigational vaccine that could address three respiratory viruses in one.

UniSC Clinical Trials staff will enroll participants in a Moderna phase 1 trial of a combination investigational vaccine for COVID-19, influenza, and respiratory syncytial virus (RSV) at its South Bank clinic in Brisbane.

This will be the third time UniSC Clinical Trials is conducting a trial for Moderna to evaluate their mRNA technology.

Principal Investigator Dr Nischal Sahai will oversee the trial that will assess the safety and immunogenicity of the investigational vaccine.

Dr Sahai said the study presented the opportunity to evaluate the potential of investigational combination mRNA vaccines.

“The investigational vaccine will be evaluated to see if it can help to reduce the burden of respiratory disease and offer the community the opportunity to be vaccinated for common respiratory viruses with one single dose and a yearly booster thereafter,” Dr Sahai said.

“This is an investigational mRNA vaccine which contains acids that are naturally found in our body's cells. We hope that it will instruct the body to make antibodies when exposed to these three respiratory viruses.”

The study requires healthy volunteers between the ages of 50 and 75. Participants will be asked to attend seven clinic visits and eight phone calls over a period of up to 13 months.

“The investigational vaccine will be administered by injection into the upper arm muscle, like the annual influenza vaccine,” Dr Sahai said.

“It is hoped that by combining the vaccines for these three respiratory viruses there could be increased protection for older people due to the ease at which it could be accessed; much like paediatric vaccines, as well as potentially increasing compliance,” he said.

Eligible participants will be paid for their time on the study. Those interested in volunteering can find more information at

Related articles

USC Clinical Trials seeks healthy volunteers for malaria study in Brisbane
6 Apr 2022

USC Clinical Trials will partner with Geneva-based Medicines for Malaria Venture and QIMR Berghofer Medical Research Institute in Brisbane to test the activity of an antimalarial drug in humans who are infected with m

Trials for possible cholesterol vaccine to begin in Moreton Bay
25 May

A possible vaccine for elevated cholesterol is set to be trialled in Moreton Bay at the University of the Sunshine Coast.

Community can help with next vaccines as flu reaches pre-pandemic levels
4 May

As influenza infections in Australia return to pre-pandemic levels, the University of the Sunshine Coast Clinical Trials Centre seeking people to help with the development of the next generation of vaccines.

Search results for Recent news